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Father: John Sr. Ison
Born: 1675
Marr: 1710
Died: 1759, Va
Mother: Martha Elizabeth Huff
Born: 1676
Died:
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 | John Ison,(1712) 
Born: 1712 - Nanesemond, Amherst Co, Va
Marr: 1736 - , Amherst, Virginia
Died: AFT 1769 - , Tyrone, n.c.
Other Spouses:
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 | Rebecca Lucy Jones 
Born: 1713 - , Amherst Co, Va
Died: - Tyrone, Nc
Other Spouses:
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 | 1. Mary Isom  Born: ABT 1761 - , Of Wythe, Va Marr: 1770 - John Ison,(1752) Died: - |  | 2. Archibald Isom  Born: 1730 - , , Amherst, Va Marr: - Died: - |  |
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 | 3. Ira Isom  Born: ABT 1737 - , Scott, Virginia Marr: - Died: - |  | 4. James Isom  Born: 1739 - , Scott, Virginia Marr: - Died: 1 Jul 1765 - , Amherst Co., Va |  |
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 | 5. William Isom  Born: 1740 - , Scott, Virginia Marr: - Died: 12 Feb 1840 - , Amherst Co., Va |  | 6. Joshua Isom  Born: 1742 - , Scott, Virginia Marr: - Died: - |  |
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 | 7. Charles Isom,(1744)  Born: 1744 - , Scott, Virginia Marr: - Died: 1833 - |  | 8. Elizabeth Isom,(1746)  Born: 1746 - , Scott, Virginia Marr: - Died: 1839 - |  |
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 | 9. Elijah Isom  Born: 1 Oct 1759 - , Scott, Virginia Marr: - Died: - |  | 10. George Isom  Born: 1 Oct 1759 - , Scott, Virginia Marr: - Died: - |  |
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 | 11. Jonathan Ison  Born: 1748 - , Amherst Co, Va Marr: - Died: 8 May 1882 - |  | 12. Samuel Ison  Born: 1749 - , Amherst Co, Va Marr: - Died: 1850 - Big Sandy, , Ky |  |
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 | 13. John Ison,(1752)  Born: 5 Apr 1752 - , Amherst Co, Va Marr: 1770 - Mary Isom Died: ABT 1830 - , Of Grayson, Va |  |
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